Introduction: protein metabolism (Kumar et al. 2011). Impairment of

Introduction:

Diabetes
mellitus, commonly known as diabetes, is a dysfunction of the endocrine system
which causes defects in insulin secretion, and impairs glucose, lipid and
protein metabolism (Kumar et al. 2011). Impairment of insulin secretion and
defects in insulin action frequently coexist in the same patient, and often
remain unclear that of which abnormality is the primary cause of the
hyperglycemia. Polyuria, polydipsia,
weight loss, sometimes with polyphagia, and blurred vision are the some of the
symptoms of marked hyperglycemia. If left untreated, it may cause many
complications such as affect to eyes, kidneys, nerves, and blood vessels
(Forbes & Cooperet al, 2013) and is considered as one of the ?ve leading
causes of death in the world. Many appreciable progresses have been made in the
management of diabetes using conventional drugs and management strategies but
its complications continue to be a major medical problem. Most of the synthetic
oral hypoglycaemic drugs available for the treatment of diabetes have serious
side-effects and/or cannot be used during pregnancy, and are also costly
(Kumari et al. 2013).

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Nowadays,
compared to drug therapy, a resurgence of interest in using diet to manage and
treat diabetes millitus has emerged in recent years. People are now seeking for
natural and herbal sources for the management of the disease. Spices are
natural herbs and possess hypoglycemic, hypolipidemic, antioxidant and other
useful effects on human health. Spices have minimal or no side-effects rather
give synergistic actions (Panda et al.2013).

In
this study, fourteen types of spices were used in a combination, to evaluate
their effect in lowering blood glucose level. Many of the spices have
antidiabetic effect individually, but when they are used in combination, their
effect is expected to be increased (Gloria A. et al,2015). Allium sativum (garlic)
contains bioactive component allicin, which gives antioxidant properties as
well as hypoglycemic and anticancer effect. (Thomson et al, 2007). Quercetin is
another bioactive component found in Allium cepa L. (onion) that has  hypoglycemic effect (Caridiet al, 2007). Allium
cepa also facilitates bowel movements and erections, and relieve headaches,
coughs, snakebite, and hair loss (“About Onions: 2013-09-13). Zingiber officinale
(Ginger) shows anti-diabetic due to have bioactive component B-type procyanidin
as well as possess anti-cancer, anti-inflammatory, anti-Alzheimer and
antioxidant effect (Rahnmanet al, 2014). Curcuma longa (turmeric) has another
bioactive component curcumin which also shows anti diabetic effect (Chuensamarnet
al, 2012).

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Conflict
of Interest:

The
authors declares no conflict of interest. The authors are solely responsible
for the content of the paper.

Acknowledgement:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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